Article

Functional Analysis of Ectodysplasin-A Mutations in X-Linked Non-Syndromic Hypodontia and Possible Involvement of X-Chromosome Inactivation

2021-03-06

Abstract excerpt

<h4>Background: </h4> Mutations of the Ectodysplasin-A (EDA) gene are generally associated with other developmental anomalies (syndrome hypohidrotic ectodermal dysplasia) or as an isolated condition (non-syndromic tooth agenesis). The influence of EDA mutations on dentinogenesis and odontoblast differentiation have not been reported. The aim of the present study was to identify genetic clues for familial nonsyndro...

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Literature Corpus work: e18e91c9-1cbf-5a55-b123-0c25d21d487c
DOI: 10.21203/rs.3.rs-270895/v1

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