Article

An aptamer targeting TfR1 enhances ASO delivery to muscle tissue

2026-07-19

Abstract excerpt

Oligonucleotide based therapeutics continue to rise as a significant class of medicines for the treatment of human disease. However, achieving delivery to non-hepatic tissues remains a challenge in the field. While substantial advances have been realized, largely through the use of antibody or protein based targeting agents to tissues including muscle and the CNS, these large protein agents present complications i...

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Literature Corpus work: e187109d-e363-5eca-83fb-f5b41b15b3fb
DOI: 10.64898/2026.07.13.737509

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