Back to search

Article

Steroidogenic activity of methylated resveratrol analogue 3,4,5,4′-tetramethoxystilbene (DMU-212) in human luteinized granulosa cells in a primary three-dimensional in vitro model

2023-03-02

Abstract excerpt

<title>Abstract</title> <p>Purpose One of the main functions of granulosa cells (GCs) is the secretion of steroid hormones. Resveratrol is a natural polyphenol, known for its beneficial health effects, such as improving reproductive health. However, its application is limited due to poor bioavailability. Methoxy derivative of resveratrol (DMU-212) was shown to be more lipophilic, and consequently more bioavailab...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
e1361d8b-4f57-5592-87db-12513b12fbfa
DOI
10.21203/rs.3.rs-2628184/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Steroidogenic activity of methylated resveratrol analogue 3,4,5,4′-tetramethoxystilbene (DMU-212) in human luteinized granulosa cells in a primary three-dimensional in vitro modelDOI 10.21203/rs.3.rs-2628184/v1
Resveratrol Targets a Variety of Oncogenic and Oncosuppressive Signaling for Ovarian Cancer Prevention and TreatmentSemantic proximity
Resveratrol promotes expression of SIRT1 and StAR in rat ovarian granulosa cells: an implicative role of SIRT1 in the ovarySemantic proximity
Modulation of steroidogenesis by Actaea racemosa and vitamin C combination, in letrozole induced polycystic ovarian syndrome rat model: Promising activity without the risk of hepatic adverse effectSemantic proximity
Resveratrol addition to in vitro maturation and in vitro culture media enhances developmental competence of sheep embryosSemantic proximity
Resveratrol analogue 3,4,4′,5-tetramethoxystilbene inhibits growth, arrests cell cycle and induces apoptosis in ovarian SKOV‐3 and A-2780 cancer cellsSemantic proximity
Between the Devil and the Deep Blue Sea—Resveratrol, Sulfotransferases and Sulfatases—A Long and Turbulent Journey from Intestinal Absorption to Target CellsSemantic proximity
Unlocking the Green Solution: Synergistic Effects of Progesterone and Brassinosteroids in Enhancing Progesterone Phytoremediation and Antioxidant Capacity of Solanum nigrum L.Semantic proximity
Chitosan/Alginate-loaded Astragalus hamosus shows ameliorating effects on lipid profile, inflammatory and hormonal parameters, and reduces miRNA-222 expression in Polycystic Ovary Syndrome RatsSemantic proximity
The Effect of 4′-hydroxy-3,4,5-trimetoxystilbene, the Metabolite of Resveratrol Analogue DMU-212, on Growth, Cell Cycle and Apoptosis in DLD-1 and LOVO Colon Cancer Cell LinesSemantic proximity
Resveratrol Inhibits Development of Experimental Endometriosis In Vivo and Reduces Endometrial Stromal Cell Invasiveness In Vitro1Semantic proximity
Unlocking the Green Solution: Progesterone and Brassinosteroids Synergistically Enhance Progesterone Phytoremediation and Antioxidant Capacity of Solanum nigrum L.Semantic proximity
Characterization of the vitamin D endocrine system in human sebocytes in vitroSemantic proximity
Select a neighboring publication to make it the new centre.