Article

Overexpression of Lias Gene Alleviates Pulmonary Injury Induced by fine particulate matter in Mice

2022-05-27

Abstract excerpt

Oxidative stress, inflammation is generally regarded as important toxicity mechanisms induced by fine particulate matter (PM 2.5 ). The antioxidant baselines of human body affect the intensity of oxidative stress in vivo. Our study aimed to evaluate the role of endogenous antioxidant capacity in PM 2.5 -induced pulmonary injury using a novel mouse model ( Lias H/H ) which approximately increased 150% endogenous an...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e10843c5-4ca9-52c8-84b2-9169b3867d91
DOI: 10.21203/rs.3.rs-1599359/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Overexpression of Lias Gene Alleviates Pulmonary Injury Induced by fine particulate matter in MiceDOI 10.21203/rs.3.rs-1599359/v1Read

MicroRNA-760 Resists Ambient PM2.5-induced Lung Injury Through Upregulating Heme-oxygenase 1 ExpressionSemantic proximity Read

PM2.5 inhibits SOD1 expression by up-regulating microRNA-206 and promotes ROS accumulation and disease progression in asthmatic miceSemantic proximity Read

Particulate Matter-Induced Oxidative Stress – Recent Mechanistic Insights from In Vitro StudiesSemantic proximity Read

TLR4 knock out alleviate both lung and liver inflammation caused by short-time exposure to PM2.5Semantic proximity Read

Assessment on the lung injury of mice posed by airborne PM2.5 collected from developing area in China and associated molecular mechanisms: from histopathology to integrated transcriptome analysisSemantic proximity Read

Particulate Matter Exposure-Induced Cholesterol Metabolism Disorder In Lung Epithelial CellsSemantic proximity Read

Environmentally Persistent Free Radical Promotes Lung Cancer Progression Via Regulating The Expression Profile of miRNAsSemantic proximity Read

Anti-inflammatory effects of H2S during acute bacterial infection: a reviewSemantic proximity Read

Biochemical Evidence of PM2.5 Critical Components in the Induction of Myocardial Fibrosis in MiceSemantic proximity Read

Ganduqing attenuates PM2.5-induced lung injury via regulating the pulmonary microbiota and metabolic profilesSemantic proximity Read

PM2.5 exposure increase dry eye disease risks through corneal epithelial inflammation and mitochondrial dysfunctionsSemantic proximity Read

Regulation of glutathione in inflammation and chronic lung diseases.Semantic proximity Read