Back to search

Article

The segmented flavivirus Alongshan virus reduces mitochondrial mass via degrading STAT2 to suppress innate immune response

2024-03-07

Abstract excerpt

Alongshan virus (ALSV) is a newly discovered pathogen of the Flaviviridae family, characterized by a multi-segmented genome distantly related to the canonical flaviviruses. Understanding the pathogenic mechanism of the emerging segmented flavivirus is crucial for the development of intervention strategies. Here we show that ALSV can infect multiple mammalian cells and induces the expression of antiviral genes. Mo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
e0f9d576-1195-5818-b012-09fb57e3809a
DOI
10.1101/2024.03.06.583679
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The segmented flavivirus Alongshan virus reduces mitochondrial mass via degrading STAT2 to suppress innate immune responseDOI 10.1101/2024.03.06.583679
NSs: the multifaceted bunyavirus virulence factorSemantic proximity
The Role of Mitophagy in Viral InfectionSemantic proximity
The SFTSV Nonstructural Proteins Induce Autophagy to Promote Viral Replication via Interaction with VimentinSemantic proximity
SFTSV nucleoprotein mediates DNA sensor cGAS degradation to suppress cGAS-dependent antiviral responsesSemantic proximity
A Comprehensive Review of Coronavirus Non-Structure Protein 6 on Structure, Functions, Mechanisms and Its Implications for Antiviral Research.Semantic proximity
Suppression of Type I Interferon Signaling by Flavivirus NS5Semantic proximity
A Look into Bunyavirales Genomes: Functions of Non-Structural (NS) ProteinsSemantic proximity
Viral strategies for triggering and manipulating mitophagySemantic proximity
Systematic functional analysis of SARS-CoV-2 proteins uncovers viral innate immune antagonists and remaining vulnerabilitiesSemantic proximity
The nonstructural protein 1 of respiratory syncytial virus hijacks host mitophagy as a novel mitophagy receptor to evade the type I IFN response in HEp-2 cellsSemantic proximity
Pressure to evade cell-autonomous innate sensing reveals interplay between mitophagy, IFN signaling, and SARS-CoV-2 evolutionSemantic proximity
Suppression of MDA5-mediated antiviral immune responses by NSP8 of SARS-CoV-2Semantic proximity
Select a neighboring publication to make it the new centre.