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<i>Candida albicans</i> enhances melanoma cell aggressiveness through p38-MAPK and HIF-1α pathways and metabolic reprogramming

2025-01-18

Abstract excerpt

Recent studies have increasingly focused on the role of fungi, including Candida albicans , in carcinogenesis. Since C. albicans is a component of the human microbiota, particularly on the skin, we investigated its effect on the phenotype and signalling pathways of melanoma cells. Assays for migration, adhesion, angiogenesis, and hepatic metastasis showed that C. albicans promotes a more malignant phenotype in...

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Literature Corpus work
e06440a5-ac82-5f2e-9700-f80b6a1fb677
DOI
10.1101/2025.01.17.633543
Open publication

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<i>Candida albicans</i> enhances melanoma cell aggressiveness through p38-MAPK and HIF-1α pathways and metabolic reprogrammingDOI 10.1101/2025.01.17.633543
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