Integrated transcriptomic analysis reveals a lncRNA-miRNA-TF-mRNA regulatory network underlying quercetin’s anti-hepatocellular carcinoma effects

Abstract excerpt

<title>Abstract</title> <p> Background Quercetin (QUR) exhibits multiple pharmacological activities against hepatocellular carcinoma (HCC). Competing endogenous RNA (ceRNA) networks and transcription factors (TFs) play critical roles in oncogenesis and cancer progression, however, the integrated ceRNA- and TF-mediated mechanisms of QUR in HCC treatment remain largely unknown. Methods The anti-proliferative, an...

Topics

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• Antineoplastic Agents
• Autophagy in Disease and Therapy
• Cancer-related molecular mechanisms research
• Drug Design
• Genetic Predisposition to Disease
• MicroRNA in disease regulation
• Neoplasms
• RNA, Long Noncoding

Identifiers and source

Literature Corpus work

e059954f-1462-5a7b-9a2b-be9a393b5bb6

DOI

10.21203/rs.3.rs-8329255/v1