Article

Continuous ZnO nanoparticle exposure induces melanoma-like skin lesions in epidermal barrier dysfunction model mice through anti-apoptotic effects mediated by the oxidative stress–activated NF-κB pathway

2021-11-01

Abstract excerpt

<title>Abstract</title> <p>Background: Increasing interest in the hazardous properties of zinc oxide nanoparticles (ZnO NPs), commonly used as ultraviolet filters in sunscreen, has driven efforts to study the percutaneous application of ZnO NPs to diseased skin; however, in-depth studies of toxic effects on melanocytes under conditions of epidermal barrier dysfunction remain lacking. <h4>Methods:</h4> Epidermal b...

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Literature Corpus work: e043bf28-7777-557a-8ad7-511339e66de3
DOI: 10.21203/rs.3.rs-1000478/v1

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