Article

A Comprehensive Study on Surveillance Outcomes of a Male Population Carrying Pathogenic/Likely pathogenic Variants associated with Hereditary Breast Cancer Syndromes at a Portuguese Tertiary Hospital

2023-04-03

Abstract excerpt

Men born with pathogenic/likely pathogenic variants in genes associated with the Hereditary Breast and Ovarian Cancer Syndrome have a higher risk to develop breast cancer and other cancers (such as prostate cancer) and should undergo adequate surveillance protocols in highly specialized Centers. A retrospective study was conducted to assess these genetic variants’ epidemiological and phenotypical manifestations in...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e03e6fc6-8cc9-5497-a91b-3f016576f355
DOI: 10.21203/rs.3.rs-2758501/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A Comprehensive Study on Surveillance Outcomes of a Male Population Carrying Pathogenic/Likely pathogenic Variants associated with Hereditary Breast Cancer Syndromes at a Portuguese Tertiary HospitalDOI 10.21203/rs.3.rs-2758501/v1Read

A comprehensive study on surveillance outcomes of a male population followed at a hereditary breast cancer high-risk consultation at a Portuguese tertiary hospital.Semantic proximity Read

Interdisciplinary risk counseling for hereditary breast and ovarian cancer: real-world data from a specialized center.Semantic proximity Read

[Who must be referred for genetic counseling?]Semantic proximity Read

Evaluation of family history in individuals with heterozygous BRCA pathogenic variants diagnosed with breast or ovarian cancer in a single center in Italy.Semantic proximity Read

BRCA1 and BRCA2 mutational profile and prevalence in hereditary breast and ovarian cancer (HBOC) probands from Southern Brazil: Are international testing criteria appropriate for this specific population?Semantic proximity Read

Atypical cancer risk profile in carriers of Italian founder BRCA1 variant p.His1673del: Implications for classification and clinical management.Semantic proximity Read

Incidental findings in a series of 2500 gene panel tests for a genetic predisposition to cancer: Results and impact on patients.Semantic proximity Read

Familial history and prevalence of BRCA1, BRCA2 and TP53 pathogenic variants in HBOC Brazilian patients from a public healthcare service.Semantic proximity Read

Genetic testing for familial hyperparathyroidism: clinical-genetic profile in a Mediterranean cohortSemantic proximity Read

Identification of Germline Variants in Patients with Hereditary Cancer Syndromes in Northeast MexicoSemantic proximity Read

Medical knowledge and information needs among women with pathogenic variants in moderate-risk genes for hereditary breast cancer attending genetic counseling at an academic hospital in Germany-A qualitative approach.Semantic proximity Read

Five Years of Multidisciplinary Care in Hereditary Cancer: Our Experience in a Spanish University Hospital.Semantic proximity Read