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Identification of ROS and KEAP1 related genes and verified targets of α-hederin induce cell death for CRC

2023-10-17

Abstract excerpt

In this study, we analyzed and verified Differentially Expressed Genes (DEGs) in ROS and KEAP1 crosstalk in oncogenic signatures using GEO datasets (GSE4107, GSE41328). Multiple pathway enrichment analyses were finished based on DEGs. The genetic signature for colorectal adenocarcinoma (COAD) was identified by using the Cox regression analysis. Kaplan–Meier (KM) survival and receiver operating characteristic (ROC)...

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Literature Corpus work
e0126558-a72a-5ce6-b23d-a59291604fb2
DOI
10.21203/rs.3.rs-3439329/v1
Open publication

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