Article

Comparative Exome Capture Methods to Investigate Genes Involved in Hypopituitarism in a Brazilian Population

2021-03-01

Abstract excerpt

Whole Exome Sequencing (WES) has been a useful tool to improve molecular diagnosis in hypopituitarism, leading to the discovery of at least 8 new genes in the last 7 years. However, some genes associated with hypopituitarism show low coverage in this methodology, limiting its use for molecular diagnosis. Our objective is to compare three library prepping kits, NimbleGen (Roche), SureSelect (Agilent) and Nextera (I...

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Literature Corpus work: dfec50ae-892b-503b-84c5-4e412d7d323c
DOI: 10.21203/rs.3.rs-244377/v1

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