Article

Downregulation of acetyl-CoA carboxylase suppresses the malignant progression of oral cancer

2024-07-23

Abstract excerpt

In this study, we aimed to investigate the specific role of the acetyl-CoA carboxylase (ACACA) gene in Oral squamous cell carcinoma (OSCC). we constructed Human Tongue Carcinoma Cell Line (SAS cell line) with low ACACA expression and evaluated changes in their cell cycle, proliferation, and metabolite levels. Furthermore, the effect of ACACA on tumor formation in vivo was determined. ACACA knockdown significantly...

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Literature Corpus work: dfbb92df-6bec-5d0c-bfc0-aa7c05bcd2dd
DOI: 10.1101/2024.07.21.604509

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