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TCF12-Related Bicoronal Craniosynostosis Complicated by a Large Middle Fossa Arachnoid Cyst and Developmental Regression: Case Report and Literature Review

2026-03-25

Abstract excerpt

<title>Abstract</title> <p>Pathogenic variants in Transcription Factor 12 (TCF12) have been identified as genetic causes of craniosynostosis. The phenotypic spectrum of TCF12-related craniosynostosis is broad and remains incompletely understood. Herein, we report a case of a 2-month old male with a heterozygous pathogenic variant of TCF12 (c.1267C > T; pArg423*) and bicoronal craniosynostosis. He underwent bicoro...

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Literature Corpus work: dfb028ac-da5a-5eb8-ac8b-5678a49b9eb2
DOI: 10.21203/rs.3.rs-8866894/v1

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