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Virtual control arms for paediatric myopia trials: external validation of axial-elongation models

2026-08-23

Abstract excerpt

Clinical relevance: Validated virtual control arms may provide population-level estimates of treatment effect and reduce reliance on untreated control allocations in myopia trials. <h4>Background:</h4> Untreated single-vision control arms in paediatric myopia efficacy trials are increasingly difficult to justify and retain. Several published models predict untreated childhood axial elongation by region or ethnicit...

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Literature Corpus work
df234f58-d7e2-5c9a-b836-5b0d0319ca35
DOI
10.64898/2026.08.21.26360973
Open publication

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Virtual control arms for paediatric myopia trials: external validation of axial-elongation modelsDOI 10.64898/2026.08.21.26360973
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