Article

Mutation Pathogenicity Prediction by a Biology Based Explainable AI Multi-Modal Algorithm

2024-06-05

Abstract excerpt

Most known pathogenic mutations occur in protein-coding regions of DNA and change the way proteins are made. Deciphering the protein structure therefore provides great insight into the molecular mechanisms underlying biological functions in human disease. While there have recently been major advances in the artificial intelligence-based prediction of protein structure, the determination of the biological and clini...

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Literature Corpus work: def6c557-903b-5320-868b-7162147dd757
DOI: 10.1101/2024.06.05.24308476

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