Article

Ecopipam (EBS-101) as a Novel Non-D2 Therapy for Tourette Syndrome: A Systematic Review and Meta-analysis of Prospective Clinical Studies

2026-07-30

Abstract excerpt

<h4>Background: </h4> Tourette syndrome (TS) is a neurodevelopmental disorder characterized by persistent motor and vocal tics. Current treatments mainly target dopamine D2 receptors but are often limited by adverse effects. Ecopipam, a selective dopamine D1 receptor antagonist, has emerged as a potential non-D2 therapeutic alternative. <h4>Methods:</h4> PubMed, Embase, Cochrane Library, Google Scholar, and Clinic...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: de2e3637-1a3b-5877-9c11-34d9af9fbdc0
DOI: 10.20944/preprints202607.2220.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Ecopipam (EBS-101) as a Novel Non-D2 Therapy for Tourette Syndrome: A Systematic Review and Meta-analysis of Prospective Clinical StudiesDOI 10.20944/preprints202607.2220.v1Read

Gilles de la Tourette syndrome: the complexities of phenotype and treatment.Semantic proximity Read

Sex Differences in People with Tourette Syndrome and Persistent Motor or Vocal Tic Disorder in the Tourette Association of America International Consortium for Genetics DatabaseSemantic proximity Read

Clinical phenotypes and early treatment escalation in pediatric acute drug-induced dystonia: A tertiary emergency department cohort study.Semantic proximity Read

Cariprazine in an Adolescent with Tourette Syndrome with Comorbid ADHD and Depression: A Case ReportSemantic proximity Read

A refresher on Tourette syndrome.Semantic proximity Read

Neurobehavioral aspects, pathophysiology, and management of Tourette syndrome.Semantic proximity Read

Treating Tourette Together: An Agenda for Patient-Centered Research Focused on Comprehensive Behavior Therapy for TicsSemantic proximity Read

Phenotype Development in Adolescents With Tourette Syndrome: A Large Clinical Longitudinal Study.Semantic proximity Read

Advances in Tourette SyndromeSemantic proximity Read

Considerations of natural history and pathophysiology in the psychopharmacology of Tourette's syndrome.Semantic proximity Read

A personal 35 year perspective on Gilles de la Tourette syndrome: prevalence, phenomenology, comorbidities, and coexistent psychopathologies.Semantic proximity Read