Article
Waves of Maturation and Senescence in Micro-Structural MRI Markers of Human Cortical Myelination over the Lifespan
2018-05-03
Abstract excerpt
Seminal human brain histology work has demonstrated developmental waves of myelination. Here, using a micro-structural magnetic resonance imaging (MRI) marker linked to myelin, we studied fine-grained age differences to deduce waves of growth, stability, and decline of cortical myelination over the life-cycle. In 484 participants, aged 8-85 years, we fitted smooth growth curves to T1- to T2-weighted ratio in each...
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Identifiers and source
- Literature Corpus work
- db4279c1-678f-5d7f-bb45-add5e5ceede2
- DOI
- 10.1101/314195
