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Impaired urease-mediated alkali generation following radiotherapy in head and neck cancer patients: a pilot salivary biochemical analysis

2026-06-01

Abstract excerpt

<title>Abstract</title> <p>Introduction Radiotherapy for head and neck cancers is associated with significant alterations in the oral environment, including salivary dysfunction. Urease-mediated hydrolysis of urea represents a key alkalinogenic pathway that contributes to plaque pH homeostasis. However, its behaviour across different stages of radiotherapy remains insufficiently explored. This study aimed to eva...

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Literature Corpus work
dae5665c-70b9-54ab-95d7-3d5e1f2ae401
DOI
10.21203/rs.3.rs-9602208/v1
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Impaired urease-mediated alkali generation following radiotherapy in head and neck cancer patients: a pilot salivary biochemical analysisDOI 10.21203/rs.3.rs-9602208/v1
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