Identification of Prognostic Biomarker Signatures and Candidate Drugs in Colorectal Cancer: Insights from Systems Biology Analysis

Abstract excerpt

<h4>Background: </h4> and objectives: Colorectal cancer (CRC) is the second most common cause of cancer-related death in the world, but early diagnosis ameliorates the survival of CRC. This report directed to identify molecular biomarker signatures in CRC. <h4>Materials and Methods:</h4> We analyzed two microarray datasets (GSE35279 and GSE21815) from Gene Expression Omnibus (GEO) to identify mutual differentially...

Topics

Open a Topic to create a Post that cites this publication.

• 14-3-3 protein interactions
• ATP Synthase and ATPases Research
• Bioinformatics and Genomic Networks
• Cancer Mechanisms and Therapy
• Computational Drug Discovery Methods
• Ferroptosis and cancer prognosis
• Hepatocellular Carcinoma Treatment and Prognosis
• Mechanisms of cancer metastasis

Identifiers and source

Literature Corpus work

dab2f840-4ed0-5fa5-9598-126894d9fb4b

DOI

10.20944/preprints201812.0018.v2