Article

Age-Stratified ICU Mortality Is Systematically Miscalibrated in Published Clinical Estimates: Cross-Validated Evidence from 201,905 Encounters Across Two Independent Datasets

2026-05-04

Abstract excerpt

<title>Abstract</title> <p> <bold>Background.</bold> Clinical decision support tools embed condition-specific ICU mortality estimates derived from age-unstratified populations. Whether these match observed mortality in age-stratified high-risk subpopulations has not been systematically tested across independent datasets. <bold>Methods.</bold> Automated outlier detection applied to MIMIC-IV v3.1 (65,241 first...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: da1598d2-5758-543c-9fcd-e4d932ed73a7
DOI: 10.21203/rs.3.rs-9518778/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Age-Stratified ICU Mortality Is Systematically Miscalibrated in Published Clinical Estimates: Cross-Validated Evidence from 201,905 Encounters Across Two Independent DatasetsDOI 10.21203/rs.3.rs-9518778/v1Read

Differences in Mortality in Critically Ill Elderly Patients During the Second COVID-19 Surge in EuropeSemantic proximity Read

How Are Researchers Using MIMIC? A Methods-Focused Review of Studies in Critical CareSemantic proximity Read

Estimating excess 1- year mortality from COVID-19 according to underlying conditions and age in England: a rapid analysis using NHS health records in 3.8 million adultsSemantic proximity Read

The long-term mortality rate in older ICU patients compared to the general populationSemantic proximity Read

Risk factors for mortality among hospitalized patients with COVID-19Semantic proximity Read

Derivation and Validation of a Clinical Deterioration Early Warning System (Cdews) Score in Hospital InpatientsSemantic proximity Read

In-hospital mortality of older patients with COVID-19 throughout the epidemic waves in the Great Paris Area: A multicenter cohort studySemantic proximity Read

Machine learning uncovers blood test patterns subphenotypes at hospital admission discerning increased 30-day ICU mortality rates in COVID-19 elderly patientsSemantic proximity Read

Systematic evaluation and external validation of 22 prognostic models among hospitalised adults with COVID-19: An observational cohort studySemantic proximity Read

Multicenter analysis of COVID-19 hospitalizations and stacking machine learning algorithms for prediction of high-risk patientsSemantic proximity Read

Characteristics and outcomes of patients admitted to Swedish intensive care units for COVID-19 during the first 60 days of the 2020 pandemic: a registry-based, multicenter, observational studySemantic proximity Read