Back to search

Article

Rice Bran Extract attenuates cognitive impairment by enhancing pancreatic β-cell insulin secretion in STZ-induced diabetic rats targeting the PPARγ/PDX1 pathway

2025-01-10

Abstract excerpt

<title>Abstract</title> <p>Type I diabetes (T1D), also known as juvenile diabetes, is an autoimmune disease that causes gradual destruction of pancreatic cells and leads to intellectual disability, neuropathy, cognitive impairment, and impaired learning ability in children. Despite standard treatment with synthetic human insulin, T1D patients can maintain up to 40% of their insulin-producing islets. PPARγ recepto...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
d8a0568c-de8c-5bf5-9a4d-e7ef752325ce
DOI
10.21203/rs.3.rs-5702421/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Rice Bran Extract attenuates cognitive impairment by enhancing pancreatic β-cell insulin secretion in STZ-induced diabetic rats targeting the PPARγ/PDX1 pathwayDOI 10.21203/rs.3.rs-5702421/v1
Enhancing Cognitive Function in Diabetic Rats: The Role of Exercise and Selenium Nanoparticles in Hippocampal ProtectionSemantic proximity
Antidiabetic Properties and Possible Mechanism of the Traditional Chinese Medicine Yi Qi Yang Yin Recipe in Db/db MiceSemantic proximity
Positive Effects of Walnut Meal Extracts on Memory Impairment of Alzheimer's Disease Mice Induced by D-GalactoseSemantic proximity
Novel role of <i>Periploca laevigata</i> extracts as anti-diabetic and anti-inflammatory function in pancreatic β cells exposed to hyperglycaemiaSemantic proximity
Starch synthase IIIa and starch branching enzyme IIb-deficient mutant rice line ameliorates pancreatic insulin secretion in rats: screening and evaluating mutant rice lines with antidiabetic functionalities.Semantic proximity
The impact of Insulin Resistance evaluated by 20/ (fasting blood glucose × fasting C-peptide) on cognitive declined Japanese Type 2 Diabetes PatientSemantic proximity
Memory impairment and depressive-like phenotype are accompanied by downregulation of hippocampal insulin and BDNF signaling pathways in prediabetic mice.Semantic proximity
Diet Control to Achieve Euglycemia Induces Tau Hyperphosphorylation Via AMPK Activation in the Hippocampus of Diabetic RatsSemantic proximity
Effects of Carvacrol on PI3K/Akt Pathway, Glut2 and Insulin Expression in Pancreatic Cells in a Rat Model of Type 1 Diabetes MellitusSemantic proximity
Iguratimod Attenuates Diabetic Cognitive Impairment via Suppressing B Cell Activation and CD8+ T Cell CytotoxicitySemantic proximity
Gamma-aminobutyric acid for delaying type 1 diabetes mellitus: an updateSemantic proximity
Ameliorating Prediabetes Symptoms via Aerobic Exercise Combined with Green Coffee and Chlorogenic Acid Intake by Targeting MondoA-TXNIP/ARRDC4-GLUT4 Axis inHigh Fat Diet-Induced Prediabetic MiceSemantic proximity
Select a neighboring publication to make it the new centre.