Article

Development of a Prognostic Model for Sepsis Based on Gut Microbiota-Associated Genes and Identification of Potential Targets

2025-11-19

Abstract excerpt

<h4>Background</h4> Gut microbiota dysbiosis drives sepsis progression by impairing intestinal barrier function and exacerbating systemic inflammation, but the microbiota-host-immune interaction mechanisms remain unclear. <h4>Methods</h4> We integrated transcriptomic and single-cell RNA sequencing (scRNA-seq) data from the Gene Expression Omnibus (GEO) database. Differentially expressed genes (DEGs) between seps...

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Literature Corpus work: d7c98a5a-ddbd-599f-bc5c-b4fe5dec50ca
DOI: 10.1101/2025.11.17.25340434

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