Article

Protein-coding repeat polymorphisms strongly shape diverse human phenotypes

2021-01-20

Abstract excerpt

Hundreds of the proteins encoded in human genomes contain domains that vary in size or copy number due to variable numbers of tandem repeats (VNTRs) in proteincoding exons. VNTRs have eluded analysis by the molecular methods—SNP arrays and high-throughput sequencing—used in large-scale human genetic studies to date; thus, the relationships of VNTRs to most human phenotypes are unknown. We developed ways to estimat...

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Literature Corpus work: d72d3d99-5c37-533c-ad47-bbe91903f6c4
DOI: 10.1101/2021.01.19.427332

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