Article

Mathematical Analysis of Age‐Structured HIV‐1 Dynamics with Combination Antiretroviral Therapy

2007-01-01

Abstract excerpt

Various classes of antiretroviral drugs are used to treat HIV infection, and they target different stages of the viral life cycle. Age‐structured models can be employed to study the impact of these drugs on viral dynamics. We consider two models with age‐of‐infection and combination therapies involving reverse transcriptase, protease, and entry/fusion inhibitors. The reproductive number ${\cal R}$ is obtained, and...

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Literature Corpus work: d2ee2ad0-57da-57d2-aba7-f436b37e23de
DOI: 10.1137/060663945

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