Article

Mir-20a-5p induced WTX deficiency promotes gastric cancer progressions through regulating PI3K/AKT signaling pathway

2020-09-21

Abstract excerpt

<h4>Background: </h4> The X-linked gene WTX (also called AMER1) has been reported to function as a tumour suppressor gene in Wilms’ tumour. In our previous study, WTX expression was shown to be significantly reduced in gastric cancer (GC), but the function and mechanism associated with WTX loss had yet to be fully elucidated. <h4>Methods: </h4>: WTX expression and clinical significance were father analyzed in GC a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d2c4d26d-ddfd-5dca-b974-04fb2b94a32b
DOI: 10.21203/rs.3.rs-37466/v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Mir-20a-5p induced WTX deficiency promotes gastric cancer progressions through regulating PI3K/AKT signaling pathwayDOI 10.21203/rs.3.rs-37466/v2Read

The General Expression Analysis of WTX Gene in Normal and Cancer Tissues.Semantic proximity Read

Upregulation of LncRNA WT1-AS Inhibits Tumor Growth and Promotes Autophagy in Gastric Cancer via Suppression of PI3K/Akt/mTOR PathwaySemantic proximity Read

YY1-modulated Long Non-coding RNA SNHG12 Predicts and Promotes Gastric Cancer Metastasis via Activating miR-218-5p/YWHAZ-dependent β-catenin: A Bed to Bench ApproachSemantic proximity Read

WWP1 as a potential tumor oncogene regulates PTEN-Akt signaling pathway in human gastric carcinomaSemantic proximity Read

Identification of Gastric Cancer–Related Genes Using a cDNA Microarray Containing Novel Expressed Sequence Tags Expressed in Gastric Cancer CellsSemantic proximity Read

PKMYT1 Promotes Gastric Cancer Cell Proliferation and Apoptosis ResistanceSemantic proximity Read

Bioinformatic analysis suggests that UGT2B15 activates the Hippo‑YAP signaling pathway leading to the pathogenesis of gastric cancerSemantic proximity Read

TUBA1C: a new potential target of LncRNA EGFR-AS1 promotes gastric cancer progressionSemantic proximity Read

PTBP1 knockdown impairs autophagy flux and inhibits gastric cancer progression through TXNIP-mediated oxidative stressSemantic proximity Read

LncRNA NEAT1 Promotes Gastric Cancer Progression Through miR-17-5p/TGFβR2 Axis Up-Regulated AngiogenesisSemantic proximity Read

Application of Bioinformatics Analysis to Identify Important Pathways and Hub Genes in Ovarian Cancer Affected by WT1Semantic proximity Read

PIWIL1 Promotes Gastric Cancer via a piRNA-Independent MechanismSemantic proximity Read