Article

Integrative Analysis of Mitochondrial Dysfunction-Associated Genes in NAFLD: Diagnostic Model and Therapeutic Insights

2026-07-06

Abstract excerpt

<title>Abstract</title> <p> Non-alcoholic fatty liver disease (NAFLD) is a prevalent chronic liver condition that poses a significant global health challenge, wherein mitochondrial dysfunction is a critical factor in its pathogenesis. This study aimed to systematically identify genes associated with mitochondrial dysfunction in NAFLD by integrating datasets from the Gene Expression Omnibus (GEO), specifically GS...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d1f4f53e-20e7-5b0c-a8f2-f93ea4dee913
DOI: 10.21203/rs.3.rs-8583672/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Integrative Analysis of Mitochondrial Dysfunction-Associated Genes in NAFLD: Diagnostic Model and Therapeutic InsightsDOI 10.21203/rs.3.rs-8583672/v1Read

MCD biomarkers Egfr, Hmox1, Lgmn identified in NAFLDSemantic proximity Read

Exploration of Key Markers Driving Ferroptosis in the Progression of Non-Alcoholic Fatty Liver DiseaseSemantic proximity Read

Integrative analysis identifies oxidative stress biomarkers in non-alcoholic fatty liver disease via machine learning and weighted gene co-expression network analysisSemantic proximity Read

Bioinformatic analysis of ferroptosis-related genes and immune cell infiltration in non-alcoholic fatty liver diseaseSemantic proximity Read

Machine learning-based identification of key lipid metabolism-related genes and associated ceRNA networks in NAFLDSemantic proximity Read

Key genes associated with non-alcoholic fatty liver disease and hepatocellular carcinoma with metabolic risk factorsSemantic proximity Read

Identification of Fatty acid metabolism-Related Genes in the Progression from Non-Alcoholic Fatty Liver to Nonalcoholic fatty liver diseaseSemantic proximity Read

Bioinformatics analysis of ferroptosis-related genes and immune cell infiltration in non-alcoholic fatty liver diseaseSemantic proximity Read

Network Modeling Approaches and Applications to Unravelling Non-Alcoholic Fatty Liver DiseaseSemantic proximity Read

Identification of metabolic biomarkers associated with nonalcoholic fatty liver diseaseSemantic proximity Read

Integration of transcriptomic analysis and multiple machine learning approaches identifies NAFLD progression-specific hub genes to reveal distinct genomic patterns and actionable targetsSemantic proximity Read

Machine learning-based Algorithm Identifies Key Mitochondria-Related Genes in Non-Alcoholic SteatohepatitisSemantic proximity Read