Article

Variant location is a novel risk factor for individuals with arrhythmogenic cardiomyopathy due to a desmoplakin (<i>DSP</i>) truncating variant

2021-10-26

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Truncating variants in desmoplakin ( DSP tv) are an important cause of arrhythmogenic cardiomyopathy (ACM), however the genetic architecture and genotype-specific risk factors are incompletely understood. We evaluated phenotype, risk factors for ventricular arrhythmias, and underlying genetics of DSP tv cardiomyopathy. <h4>Methods</h4> Individuals with DSP tv and any cardiac p...

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Literature Corpus work: d1b1e7f7-72fd-5134-bb33-6caf78186f80
DOI: 10.1101/2021.10.16.21264154

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