Article

NPmatch: Latent Batch Effects Correction of Omics data by Nearest-Pair Matching

2024-05-02

Abstract excerpt

<h4>Motivation</h4> Batch effects (BEs) are a predominant source of noise in omics data and often mask real biological signals. BEs remain common in existing datasets. Current methods for BE correction mostly rely on specific assumptions or complex models, and may not detect and adjust BEs adequately, impacting downstream analysis and discovery power. To address these challenges we developed NPmatch, a nearest-ne...

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Literature Corpus work: d11a6dfa-ea72-582a-aa22-fa88fffcf085
DOI: 10.1101/2024.04.29.591524

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