Article

Complications in the study of ancient tuberculosis: non-specificity of IS6110 PCRs

2015-01-06

Abstract excerpt

The insertion sequence IS6110 is frequently used as a marker for the presence of ancient DNA (aDNA) derived from bacteria of the Mycobacterium tuberculosis complex (MTBC) in human archaeological remains. The specificity of polymerase chain reactions (PCRs) directed at IS6110 has, however, been questioned, because identical or similar elements have been identified in ‘mycobacteria other than tuberculosis (MOTT)’. T...

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Literature Corpus work: d0ba1e6c-410d-5e92-9349-098dc6241a02
DOI: 10.1179/2054892314y.0000000002

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