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The Role of Restriction-Modification Systems in the Horizontal Transfer of Carbapenem Resistance Genes in Klebsiella pneumoniae

2025-08-20

Abstract excerpt

<title>Abstract</title> <p>The rising detection rates of carbapenem-resistant <italic>Klebsiella pneumoniae</italic> (CRKP) pose significant challenges to clinical anti-infection treatments. The horizontal transfer of antibiotic resistance genes (ARGs) via plasmids is one of the primary mechanisms of acquired bacterial resistance. However, data analysis regarding the genetic mobility of these resistance genes rem...

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Literature Corpus work
cf1582d3-3bf5-5894-b506-dcac9de231b4
DOI
10.21203/rs.3.rs-7168145/v1
Open publication

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