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Gender-Based Prompt Variation and Diagnostic Accuracy of Large Language Models in Chagas Disease and Visceral Leishmaniasis: A Comparative Experimental Study

2026-04-30

Abstract excerpt

<h4>Background: </h4> Large language models (LLMs) are increasingly used as diagnostic support tools. However, their sensitivity to prompt framing (especially the gender assigned to the physician persona) is poorly understood for neglected tropical diseases (NTDs). <h4>Objective:</h4> Compare the diagnostic performance of four LLMs prompted as male or female infectious disease specialists using anonymized cases of...

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Literature Corpus work
ceaca789-6dcf-5c99-9d37-4455e8a6eb09
DOI
10.20944/preprints202604.2115.v1
Open publication

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Gender-Based Prompt Variation and Diagnostic Accuracy of Large Language Models in Chagas Disease and Visceral Leishmaniasis: A Comparative Experimental StudyDOI 10.20944/preprints202604.2115.v1
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