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Emergence of Human–Bovine Reassortant G8P[8] Rotaviruses in South Korea: Whole-Genome and Antigenic Characterization Highlighting Vaccine Mismatch Potential

2025-08-11

Abstract excerpt

Rotaviruses remain the leading cause of acute gastroenteritis in children under five years of age. In South Korea, two licensed vaccines—RotaTeq ® and Rotarix TM (RV1)—have significantly reduced the burden of rotavirus-related hospitalizations. However, vaccine-driven immune pressure has coincided with the emergence of uncommon genotypes, including G8P[8], now increasingly detected in pediatric cases. This study...

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Literature Corpus work: ce8b603e-f08a-5aa3-8af6-880eaad0d2f9
DOI: 10.22541/au.175492642.20064567/v1

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