Article

Bixin and lycopene modulation of free radical generation induced by cisplatin-DNA interaction

2009-04-01

Abstract excerpt

This work evaluated the modulation of reactive oxygen species (ROS) produced by the cisplatin-human DNA interaction in a cell-free experimental model by the carotenoids bixin and lycopene, extracted from natural dietary sources and purified through luminol- and Cypridina luciferin methoxy-analogue (MCLA)-enhanced chemiluminescence assays. The results showed that the ROS generation by DNA-cisplatin interaction was...

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Literature Corpus work: ce54c006-8b1e-581c-b0a2-4da8de22d600
DOI: 10.1016/j.foodchem.2008.08.084

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