Article

Longitudinal Analysis of CYFRA 21-1 Levels in Patients with Pulmonary Nodules: Differential Trajectories Between Benign and Malignant Cases and Impact of Tumor Resection

2026-01-13

Abstract excerpt

<h4>Background</h4> CYFRA 21-1, a cytokeratin-19 fragment, is a validated serum biomarker for non-small cell lung cancer (NSCLC). However, most studies rely on single time-point measurements, limiting its specificity in differentiating malignancy from benign pulmonary conditions. Inspired by the clinical utility of serial PSA measurements in prostate cancer, we investigated whether longitudinal trends in CYFRA 21...

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Literature Corpus work: ce0c4a38-9375-5e34-8539-2d0c5c12e467
DOI: 10.64898/2026.01.10.26343848

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