Article
scRNA-Seq and Network Pharmacology Analysis Reveal SCF/C-kit as the Targeting Mechanism of Qi Lang Formula Relieving Constipation
2024-01-03
Abstract excerpt
<h4>Background: </h4> Constipation is one of the chronic gastrointestinal functional diseases that affects the quality of life. While Qi Lang Formula (QLF) has demonstrated effectiveness in alleviating constipation symptoms, its precise mechanism remains elusive. <h4>Methods:</h4> QLF was analyzed using UPLC-MS/MS. Targets for QLF were collected from SwissADME, Herb, ITCM databases, and FC-related targets from scR...
Topics
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- Computational Drug Discovery Methods
- Flavonoids in Medical Research
- Gastrointestinal motility and disorders
- Helicobacter pylori-related gastroenterology studies
- Inflammatory Bowel Disease
- Microbial Natural Products and Biosynthesis
- Natural product bioactivities and synthesis
- Pharmacological Effects of Natural Compounds
Identifiers and source
- Literature Corpus work
- cd9e254e-93f2-5872-ba50-b72d97ad6ab5
- DOI
- 10.20944/preprints202401.0014.v1
