Article

A rare congenital anemia is caused by mutations in the centralspindlin complex

2021-04-10

Abstract excerpt

Congenital dyserythropoietic anemias (CDAs) are rare disorders characterized by morphologic abnormalities of erythroid precursors leading to ineffective erythropoiesis. CDA type III (CDAIII), characterized by erythroblast multinucleation, represents the rarest form with only ∼60 patients described in the literature. Previous work, studying two independent families, identified a causative dominant missense mutation...

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Literature Corpus work: cd03f217-764b-5b6d-9d50-27cad6fa328e
DOI: 10.1101/2021.04.07.21254990

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