Article

Disruption of the mRNA m <sup>6</sup> A writer complex triggers autoimmunity in Arabidopsis

2025-02-23

Abstract excerpt

<h4>ABSTRACT</h4> Distinguishing self from non-self is crucial to direct immune responses against pathogens. Unmodified RNAs stimulate human innate immunity, but RNA modifications suppress this response. mRNA m 6 A modification is essential for Arabidopsis thaliana viability. However, the molecular basis of the impact of mRNA m 6 A depletion is poorly understood. Here, we show that disruption of the Arabidopsi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ccfad298-0120-5bf0-9418-63b2bc39b991
DOI: 10.1101/2025.02.18.638636

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Disruption of the mRNA m <sup>6</sup> A writer complex triggers autoimmunity in ArabidopsisDOI 10.1101/2025.02.18.638636Read

Widespread premature transcription termination of <i>Arabidopsis thaliana</i> NLR genes by the spen protein FPASemantic proximity Read

Lariat debranching by RNA DEBRANCHING ENZYME 1 depends on SICKLE in <i>Arabidopsis thaliana</i>Semantic proximity Read

Role of AT1G72910, AT1G72940, and ADR1-LIKE 2 in Plant Immunity under Nonsense-Mediated mRNA Decay-Compromised Conditions at Low Temperatures.Semantic proximity Read

MiRNA and phasiRNAs-mediated regulation of TIR-NBS-LRR defense genes in <i>Arabidopsis thaliana</i>Semantic proximity Read

Dominance modifiers at the Arabidopsis self-incompatibility locus retain proto-miRNA features and act through non-canonical pathways.Semantic proximity Read

Phylogenetic and functional analyses of <i>N</i> <sup>6</sup> -methyladenosine RNA methylation factors in the wheat scab fungus <i>Fusarium graminearum</i>Semantic proximity Read

Arabidopsis AAR2, a conserved splicing factor in eukaryotes, acts in microRNA biogenesisSemantic proximity Read

<i>Arabidopsis</i> Topless-related 1 mitigates physiological damage and growth penalties of induced immunitySemantic proximity Read

The tRNA thiolation-mediated translational control is essential for plant immunity.Semantic proximity Read

A conserved small RNA-generating gene cluster undergoes sequence diversification and contributes to plant immunitySemantic proximity Read

Transposon-triggered epigenetic chromatin dynamics modulate EFR-related pathogen responseSemantic proximity Read

Key enzymes in N6-methyladenosine modification regulate plant stress tolerance by modulating mRNA stability.Semantic proximity Read