Article

Voice onset time as a specific classifier for the PIGD subtype in Parkinson's Disease, independent of non-motor symptom severity

2025-11-26

Abstract excerpt

<title>Abstract</title> <p>Background Parkinson’s disease (PD) is a heterogeneous disorder where the postural instability/gait difficulty (PIGD) subtype carries a poorer prognosis. This study investigates acoustic biomarkers to examine the complex relationship between motor deficits and non-motor symptoms (NMS) in PD subtypes. We hypothesized that distinct speech features—articulatory timing (Voice Onset Time, VO...

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Literature Corpus work: ccf67825-35bc-5a42-8382-5eff26a3c539
DOI: 10.21203/rs.3.rs-7979633/v1

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