Article

Rapid Whole Genome Sequencing Decreases Morbidity and Healthcare Cost of Hospitalized Infants

2018-01-26

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> Genetic disorders are a leading cause of morbidity and mortality in infants. Rapid Whole Genome Sequencing (rWGS) can diagnose genetic disorders in time to change acute medical or surgical management (clinical utility) and improve outcomes in acutely ill infants. <h4>METHODS</h4> Retrospective cohort study of acutely ill inpatient infants in a regional children’s hospital f...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ccdd1038-3e77-5ceb-b69a-877b099aa5f6
DOI: 10.1101/253534

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Rapid Whole Genome Sequencing Decreases Morbidity and Healthcare Cost of Hospitalized InfantsDOI 10.1101/253534Read

Rapid Genome Sequencing Compared to a Gene Panel in Critically Ill Infants with a Suspected Genetic Disorder: An Economic EvaluationSemantic proximity Read

The NSIGHT1 Randomized Controlled Trial: Rapid Whole Genome Sequencing for Accelerated Etiologic Diagnosis in Critically Ill InfantsSemantic proximity Read

Rapid genomic sequencing for genetic disease diagnosis and therapy in intensive care units: a reviewSemantic proximity Read

Rapid genome sequencing for critically ill infants: an inaugural pilot study from TurkeySemantic proximity Read

Use of Exome Sequencing for Infants in Intensive Care UnitsSemantic proximity Read

Case for genome sequencing in infants and children with rare, undiagnosed or genetic diseasesSemantic proximity Read

Rapid Whole Genome Sequencing in Critically Ill Neonates Enables Precision Medicine PipelineSemantic proximity Read

A genome sequencing system for universal newborn screening, diagnosis, and precision medicine for severe genetic diseasesSemantic proximity Read

Cost-effectiveness of exome and genome sequencing for children with rare and undiagnosed conditionsSemantic proximity Read

Long-Term Healthcare Utilization After Genomic Diagnosis in Seriously Ill ChildrenSemantic proximity Read

Rapid genomic sequencing in the NICU: Who to test and whySemantic proximity Read

Integrating rapid exome sequencing into NICU clinical care after a pilot research studySemantic proximity Read