Article

Human Trophoblasts-derived Exosomes Attenuate Doxorubicin Induced Cardiac Injury via Regulating Mir-200b and Downstream Zeb1

2020-06-09

Abstract excerpt

<h4>Purpose: </h4> Human trophoblast stem cells (TSC)have been confirmed to play a cardioprotective role in heart failure. However, whether trophoblast stem cell derived exosomes (TSC-Exos) can protect cardiomyocytes from doxorubicin (Dox) induced injury remains unclear. <h4>Methods: </h4>: In the present study, TSC-Exos were isolated from the supernatant of Human Trophoblasts using the ultracentrifugation method...

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Literature Corpus work: cc2f092f-6d2b-5ae4-ab14-87d1ef596bbf
DOI: 10.21203/rs.3.rs-33305/v1

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