Hub Targets Analysis of miRNA-mRNA-TF Network in Diabetic Cardiomyopathy

Abstract excerpt

<h4>Background: </h4> The pathogenic mechanism and development of the diabetic cardiomyopathy(DCM) has been generally explained, and it is clear that the microRNAs(miRNAs), mRNAs and transcription factors(TFs) participate in the process of the DCM disease. Yet, the hub targets of the disease progression are not clear. <h4>Methods: </h4> To figure out the problem, we downloaded data sets from the Gene Expression Om...

Topics

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• Bioinformatics and Genomic Networks
• Cardiac Fibrosis and Remodeling
• Cardiovascular Function and Risk Factors
• Galectins and Cancer Biology
• GDF15 and Related Biomarkers
• Metabolism, Diabetes, and Cancer
• MicroRNA in disease regulation
• RNA Research and Splicing

Identifiers and source

Literature Corpus work

cafbc24b-62b5-5677-b5a9-dbfc627682c4

DOI

10.21203/rs.3.rs-1013451/v1