Article

Contribution of rare and common variants to intellectual disability in a high-risk population sub-isolate of Northern Finland

2018-05-28

Abstract excerpt

The contribution of de novo and ultra-rare genetic variants in severe and moderate intellectual disability (ID) has been extensively studied whereas the genetic architecture of mild ID has been less well characterized. To elucidate the genetic background of milder ID we studied a regional cohort of 442 ID patients enriched for mild ID (>50%) from a population isolate of Finland. We analyzed rare variants using ex...

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Literature Corpus work: c99ec600-3f11-5923-adac-ce323c3bb3b3
DOI: 10.1101/332023

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