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Antiproliferative Activity, Phytochemistry, Network Pharmacology, Molecular Docking and Gene Expression Analysis of <i>Maerua edulis</i> Extracts against Human Cervical Cancer Cell Line

2025-01-08

Abstract excerpt

Maerua edulis exhibits significant antiproliferative activity against HeLa cells, with hexane and ethyl acetate extracts showing IC 50 values of 0.02% and 47.42 µ g/mL, respectively. Gas Chromatography-Mass Spectrometry (GC-MS) analysis identified key phytochemicals such as diisooctyl phthalate, squalene, and stigmasta-3,5-diene, which were associated with the regulation of apoptotic and cell cycle-related genes...

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Literature Corpus work
c8084382-8f23-5085-94c8-05b70a3b4387
DOI
10.1101/2025.01.07.631450
Open publication

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Antiproliferative Activity, Phytochemistry, Network Pharmacology, Molecular Docking and Gene Expression Analysis of <i>Maerua edulis</i> Extracts against Human Cervical Cancer Cell LineDOI 10.1101/2025.01.07.631450
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