Article

Circulating Extracellular Vesicles in Human Cardiorenal Syndrome Promote Renal Injury

2023-02-10

Abstract excerpt

<h4>Background</h4> Cardiorenal syndrome (CRS)—renal injury during heart failure (HF)—is linked to higher morbidity. Whether circulating extracellular vesicles (EVs) and their RNA cargo directly impact its pathogenesis remains unclear. <h4>Methods</h4> Using a microfluidic kidney chip model (KC), we investigated transcriptional effects of circulating EVs from patients with CRS on renal epithelial/endothelial cells...

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Literature Corpus work: c72aeb1a-0052-560e-ab1e-e35591b7f6f1
DOI: 10.1101/2023.02.07.23285599

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