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Multi-omic analysis identifies hypoalbuminemia as independent biomarker of poor outcome upon PD-1 blockade in metastatic melanoma

2024-02-23

Abstract excerpt

<title>Abstract</title> <p>We evaluated the prognostic value of hypoalbuminemia in context of various biomarkers at baseline, including clinical, genomic, transcriptomic, and blood-based markers, in patients with metastatic melanoma treated with anti-PD-1 monotherapy or anti-PD-1/anti-CTLA-4 combination therapy (n=178). An independent validation cohort (n=79) was used to validate the performance of hypoalbuminemi...

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Literature Corpus work
c6e80601-d581-55e0-982a-caaec40520d2
DOI
10.21203/rs.3.rs-3943202/v1
Open publication

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Multi-omic analysis identifies hypoalbuminemia as independent biomarker of poor outcome upon PD-1 blockade in metastatic melanomaDOI 10.21203/rs.3.rs-3943202/v1
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