Article

Treatment with buprenorphine increased the expression of norepinephrine genes in the lumbar spinal cords of methamphetamine rats

2023-02-24

Abstract excerpt

<h4>Background: </h4> METH damages neurons by releasing reactive oxygen species. Oxidative stress affects monoamine oxidase (MAO), a key enzyme in catecholamine oxidation. The pathogenesis of addiction may also be affected by MAO activity. Thus, the expression of MAO and norepinephrine (NE) genes was investigated in the lumbar spinal cord of METH rats during buprenorphine (PUB) treatment. <h4>Methods: </h4> and r...

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Literature Corpus work: c53981b1-8f55-5783-9d18-3d59a2c48663
DOI: 10.21203/rs.3.rs-2608110/v1

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