Article

A stem cell-based platform for functional analysis of genetic variants in lung disease

2025-07-31

Abstract excerpt

Advances in genetic and transcriptomic technologies have identified large numbers of genes and variants of potential importance to human disease. Determining the function of these genes and variants is a critical bottleneck in understanding disease etiology. Variants of uncertain significance (VUS) are highly prevalent in our genomes, but our ability to identify them significantly outpaces our ability to determine...

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Literature Corpus work: c5336530-bb00-5c7e-a5bf-7b4d51bdd4ca
DOI: 10.1101/2025.07.28.667211

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