Article

Validation of a Composite Mortality Endpoint in a Large, Clinico-Genomic Real-World Database of Patients with Advanced Cancer

2025-08-24

Abstract excerpt

<h4>Purpose</h4> Real-world data (RWD) from electronic health records (EHRs) and next-generation sequencing are increasingly used to study treatment effectiveness in molecularly refined patient populations. Incomplete mortality data in EHR can overestimate survival rates in RWD studies. While the National Death Index (NDI) is the gold standard for mortality data in the United States, its limited accessibility and...

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Literature Corpus work: c4f19881-00fa-577b-8061-980b7d5c3075
DOI: 10.1101/2025.08.20.25334011

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