Article

Protocol for standardized minimally invasive mouse models of bisphosphonate-related and radiation-induced jaw osteonecrosis

2026-07-03

Abstract excerpt

<h4>SUMMARY</h4> This protocol describes a standardized and reproducible minimally invasive approach for establishing mouse models of bisphosphonate-related osteonecrosis of the jaw (BRONJ) and osteoradionecrosis of the jaw (ORNJ). The method combines a unified low-trauma oral surgical procedure with disease-specific injury induction strategies to generate robust and clinically relevant models of jaw osteonecrosi...

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Literature Corpus work: c4cfdd54-c9d0-5e5a-9959-fb10d6c35490
DOI: 10.64898/2026.06.28.735116

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