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Efficacy and safety of a single-injection BDDE-crosslinked hyaluronic acid versus a three- injection hyaluronic acid for knee osteoarthritis: A multicenter, double-blind, randomized, noninferiority study

2026-08-07

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> LBSA0103 (Synovian <sup>®</sup> ) is a high molecular weight single-injection intra-articular hyaluronic acid product crosslinked by 1,4-butanediol diglycidyl ether (BDDE). This randomized, double-blind, multi-center, non-inferiority study was conducted to evaluate the efficacy and safety of this single-injection intra-articular hyaluronic acid (LBSA0103) c...

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Literature Corpus work
c4b3558b-10e5-5715-a853-78d939348a5d
DOI
10.21203/rs.3.rs-10419108/v1
Open publication

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Efficacy and safety of a single-injection BDDE-crosslinked hyaluronic acid versus a three- injection hyaluronic acid for knee osteoarthritis: A multicenter, double-blind, randomized, noninferiority studyDOI 10.21203/rs.3.rs-10419108/v1
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